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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvestb</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Башкортостана</journal-title><trans-title-group xml:lang="en"><trans-title>Bashkortostan Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1999-6209</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medvestb-349</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>РЕАКЦИЯ СИСТЕМЫ ГОМЕОСТАЗА ПРИ СТЕНТИРОВАНИИ ПЕРЕДНЕЙ НИСХОДЯЩЕЙ АРТЕРИИ</article-title><trans-title-group xml:lang="en"><trans-title>REACTION OF THE HOMEOSTATIC SYSTEM TO THE STENTING OF ANTERIOR DESCENDING ARTERY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плечев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Plechev</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сагатдинов</surname><given-names>Т. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Sagatdinov</surname><given-names>T. Sh.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рисберг</surname><given-names>Р. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Risberg</surname><given-names>R. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бузаев</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Buzaev</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нигматуллин</surname><given-names>М. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Nigmatullin</surname><given-names>M. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГБУЗ «Республиканский кардиологический центр»</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России; ГБУЗ «Республиканский кардиологический центр»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>29</day><month>10</month><year>2020</year></pub-date><volume>13</volume><issue>5</issue><fpage>38</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Плечев В.В., Сагатдинов Т.Ш., Рисберг Р.Ю., Бузаев И.В., Нигматуллин М.Р., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Плечев В.В., Сагатдинов Т.Ш., Рисберг Р.Ю., Бузаев И.В., Нигматуллин М.Р.</copyright-holder><copyright-holder xml:lang="en">Plechev V.V., Sagatdinov T.S., Risberg R.Y., Buzaev I.V., Nigmatullin M.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvestb.elpub.ru/jour/article/view/349">https://medvestb.elpub.ru/jour/article/view/349</self-uri><abstract><p>Уже более 50 лет в клиническую медицину вошли понятия баллонная ангиопластика и стентирование коронарных артерий. За период становления техники и разработки новых механизмов фармакологического воздействия были сформированы факторы возникновения тромбозов стентов.Цель - сравнить и проанализировать клинические лабораторные и инструментальные данные до стентирования и после него.С 2007 по 2016 гг. в ретроспективное исследование были включены 207 пациентов, которым было выполнено вмешательство в бассейне передней межжелудочковой артерии в проксимальном сегменте. Пациенты были разделены на 3 груп- пы: I группа - отсутствие осложнений (N = 139), II группа - наличие одного из осложнений (N = 54), III группа - наличие двух и более осложнений (N = 14). У всех обследованных оценивались данные биохимического и общего анализов крови, коагулограммы, эхокардиографии и др. Всего в анализе исследовали 73 параметра.На основании полученных данных значимыми для риска развития осложнений оказались 18 параметров: 14 - до про-ведения стентирования, 4 - после стентирования. При сравнении полученных цифровых значений были отмечены значимые различия в III группе при сравнении с I и II группами.Становится очевидным, что пациенты, входящие в III группу были по клинико-диагностическим данным более тяже-лые по своему коморбидному фону. У пациентов с заведомо неудовлетворительными результатами в системе гомеостаза эффект от проведенного лечения был значительно лучше.</p></abstract><trans-abstract xml:lang="en"><p>For more than 50 years, the concept of balloon angioplasty and coronary artery stenting has been included in practice. Over a period of development of the technique and new mechanisms of pharmacological influence, factors causing thrombosis of the stents have occurred.Purpose - to compare and analyze clinical and instrumental data before and after stenting.From 2007 to 2016, a total of 207 patients were included in a retrospective study. They underwent intervention in the anterior interventricular artery in the proximal segment. The patients were divided into 3 groups: Group I - no complications (N = 139),Group II - the presence of one of the complications (N = 54), III - the presence of two or more complications (N = 14). Data frombiochemical, general blood tests, coagulation, echocardiography, etc were evaluated in all patients. In total, 73 characteristics were included in the analysis.Based on the obtained data, 18 parameters were significant for the risk of complications, 14 were before stenting, 4 after. Com-paring the obtained numerical values, there are significant differences of group 3 compared with the first and second.It is becoming obvious that patients of group 3, were more severe in their comorbid background. In patients who had deliberately unsatisfactory results on the homeostasis system, the effect of the treatment was much better.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>тромбоз</kwd><kwd>рестеноз</kwd><kwd>коронарный стент</kwd><kwd>инфаркт миокарда</kwd><kwd>феномен «no-reflow»</kwd><kwd>thrombosis</kwd><kwd>restenosis</kwd><kwd>coronary stent</kwd><kwd>myocardial infarction</kwd><kwd>the phenomenon of "no-reflow"</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мышечные мосты как предикторы тромбозов стентов / В.В. Плечев [и др.] // Пермский медицинский журнал. - 2017. - Т. XXXIV, № 1. - С. 6-11</mixed-citation><mixed-citation xml:lang="en">Мышечные мосты как предикторы тромбозов стентов / В.В. Плечев [и др.] // Пермский медицинский журнал. - 2017. - Т. 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