ОНКОГИНЕКОЛОГИЧЕСКАЯ ПАТОЛОГИЯ В КОНТЕКСТЕ ПАНДЕМИИ COVID-19. ОЖИДАНИЕ И РЕАЛЬНОСТЬ

Пандемия COVID-19 оказывает влияние на все отрасли здравоохранения. В частотности, значительные сложности в области онкологии и онкогинекологии связаны как с ограничительными мерами, так и с течением злокачественных новообразований у пациентов с COVID-19. Актуальность онкогинекологических заболеваний не вызывает сомнений. Ежегодно в Российской Федерации выявляется более 50 000 пациенток с гинекологическим раком. Агрессивное течение, склонность к ранней генерализации заставляют принимать меры для лечения этих больных как можно в более ранние сроки. По рекомендациям национальных сообществ хирургов и онкологов следует максимально сокращать объемы оперативного лечения, там, где возможно производить замену хирургического лечения на альтернативные методы (химиотерапия, лучевая терапия). Безусловно, оценить результаты такого подхода возможно только через несколько лет. Необходимо время для того, чтобы статистические отчеты сформировались в условиях пандемии COVID-19. В нашей работе мы приводим данные о рекомендациях и подходах к лечению гинекологического рака в контексте пандемии COVID-19 по мнению зарубежных медицинских сообществ.

COVID-19, онкогинекология, хирургическое лечение, химиотерапия, лучевая терапия

1. Tyrrell DA, Bynoe ML. Cultivation of viruses from a high proportion of patients with colds. Lancet. 1966

2. Velavan TP, Meyer CG. The COVID-19 epidemic. Tropical Med. Int. Health. 2020

3. Cascella M, Rajnik M, Cuomo A, Dulebohn SC, Di Napoli R. Features, evaluation and treatment coronavirus (COVID-19). 2020

4. Ганцев, Ш.Х. Онкологическая служба в условиях пандемии COVID-19 (обзор литературы)/ Ш.Х. Ганцев, К.В. Меньшиков // Креативная хирургия и онкология. - 2020. - №10(3). - С. 233-240. https://doi.org/10.24060/2076-3093-2020-10-3-233-240

5. S. Kannan, P. Shaik Syed Ali, A. Sheeza, K. Hemalatha COVID-19 (Novel Coronavirus 2019) - recent trends. European Review for Medical and Pharmacological Sciences. 2020; 24: 2006-2011

6. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W, China Novel Coronavirus Investigating and Research Team. 2020. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 382:727-733. https://doi.org/10.1056/NEJMoa2001017

7. Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. 2020. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Zhonghua Liu Xing Bing Xue Za Zhi 41:145-151. https://doi.org/10.3760/cma.j.issn.0254-6450.2020.02.003

8. Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, Ren R, Leung KSM, Lau EHY, Wong JY, Xing X, Xiang N, Wu Y, Li C, Chen Q, Li D, Liu T, Zhao J, Li M, Tu W, Chen C, Jin L, Yang R, Wang Q, Zhou S, Wang R, Liu H, Luo Y, Liu Y, Shao G, Li H, Tao Z, Yang Y, Deng Z, Liu B, Ma Z, Zhang Y, Shi G, Lam TTY, Wu JTK, Gao GF, Cowling BJ, Yang B, Leung GM, Feng Z. 29 January 2020. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med https://doi.org/10.1056/NEJMoa2001316

9. Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. 2020. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Zhonghua Liu Xing Bing Xue Za Zhi 41:145-151. https://doi.org/10.3760/cma.j.issn.0254-6450.2020.02.003

10. Состояние онкологической помощи населению России в 2019 году / под ред. А.Д. Каприна, В.В.Старинского, А.О. Шахзадовой. - МНИОИ им. П.А. Герцена - филиал ФГБУ «НМИЦ радиологии» Минздрава России. - М., 2020. - 239 с

11. C. Akladiosa, H. Azaisb, M. Ballesterc, S. Bendifallahd, Pierre-Adrien Bolzee, N. Bourdel [et. al.] Recommendations for the surgical management of gynecological cancers during the COVID-19 pandemic - FRANCOGYN group for the CNGOF. Journal of Gynecology Obstetrics and Human Reproduction 49 (2020) 101729

12. Pung R, Chiew CJ, Young BE, [et al.] Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures. Lancet. 2020;395:1039e1046

13. Coronaviridae Study Group of the International Committee on Taxonomy of Viruses. The species severe acute respiratory syndromerelated coronavirus: classifying 2019-nCoV and naming it SARS-CoV2. Nat Microbiol. 2020;5:536e544

14. Liang W, Guan W, Chen R, [et al.] Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol. 2020;21(3): 335e337

15. Singh K, Hsu LY, Villacian JS, Habib A, Fisher D, Tambyah PA. Severe acute respiratory syndrome: lessons from Singapore. Emerg Infect Dis. 2003;9(10):1294e1298

16. Goh KT, Cutter J, Heng BH, et al. Epidemiology and control of SARS in Singapore. Ann Acad Med Singapore. 2006;35(5):301e316

17. Ueda M, Martins R, Hendrie PC, [et al.] Managing cancer care during the COVID-19 pandemic: agility and collaboration toward a common goal. J Natl Compr Canc Netw. 2020:1e4

18. Willan J, King AJ, Hayes S, Collins GP, Peniket A. Care of haematology patients in a COVID-19 epidemic. Br J Haematol. 2020;189(2):241e243

19. N. Ngoi, J. Lim, S. Ow, W.Y. Jen, M. Lee, W. Teo, [et al,] for the National University Cancer Institute, Singapore (NCIS). Annals of Oncology Volume 31, Issue 7, July 2020, Pages 840-843

20. Zheng M.H., Boni L., Fingerhut A. Minimally invasive surgery and the novel coronavirus outbreak: lessons learned in China and Italy. Ann Surg. In press. https://doi.org/10.1097/SLA.0000000000003924

21. American College of Surgeons. COVID-19: considerations for optimum surgeon protection before, during, and after operation. https://www.facs.org/covid-19/clinical-guidance/surgeonprotection

22. SAGES and EAES. SAGES recommendation regarding surgical response to COVID-19 crisis. https://www.sages.org/recommendations-surgical-response-covid-19

23. The Royal College of Surgeons of Edinburgh. Updated intercollegiate general surgery guidance on COVID-19. https://www.rcsed.ac.uk/news-public-affairs/news/2020/march/intercollegiate-general-surgery-guidance-on-covid-19-update

24. European Society for Gynaecological Endoscopy. Recommendations on gynaecological laparoscopic surgery during COVID-19 outbreak. https://esge.org/wp-content/uploads/2020/03/Covid19StatementESGE.pdf

25. EAU Robotic Urology Section. Guidelines during COVID-19 emergency. https://uroweb.org/wp-content/uploads/ERUS-guidelinesfor- COVID-def.pdf

26. Kwak HD, Kim SH, Seo YS, Song KJ. Detecting hepatitis B virus in surgical smoke emitted during laparoscopic surgery. Occup Environ Med 2016;73:857-63

27. Andre P, Orth G, Evenou P, Guillaume JC, Avril MF. Risk of papillomavirus infection in carbon dioxide laser treatment of genital lesions. J Am Acad Dermatol 1990;22:131-2

28. Neumann K, Cavalar M, Rody A, Friemert L, Beyer DA. Is surgical plume developing during routine LEEPs contaminated with highrisk HPV? A pilot series of experiments. Arch Gynecol Obstet 2018;297:421-4

29. Zhou Q, Hu X, Zhou J, Zhao M, Zhu X, Zhu X. Human papillomavirus DNA in surgical smoke during cervical loop electrosurgical excision procedures and its impact on the surgeon. Cancer Manage Res 2019;11:3643-54

30. Garden JM,O’BanionMK,ShelnitzLS, [et al.] Papillomavirus in the vapor of carbon dioxide laser-treated verrucae. JAMA 1988;259:1199-202

31. Sawchuk WS, Weber PJ, Lowy DR, Dzubow LM. Infectious papillomavirus in the vapor of warts treated with carbon dioxide laser or electrocoagulation: detection and protection. J Am Acad Dermatol 1989;21:41-9

32. Abramson AL, DiLorenzoTP, Steinberg BM. Is papillomavirus detectable in the plume of laser-treated laryngeal papilloma? Arch Otolaryngol Head Neck Surg 1990;116:604-7

33. Capizzi PJ, Clay RP, Battey MJ. Microbiologic activity in laser resurfacing plume and debris. Lasers Surg Med 1998;23:172-4

34. Hughes PS, Hughes AP. Absence of human papillomavirus DNA in the plume of erbium:YAG laser-treated warts. J Am Acad Dermatol 1998;38:426-8

35. Bergbrant IM, Samuelsson L, Olofsson S, Jonassen F, Ricksten A. Polymerase chain reaction for monitoring human papillomavirus contamination of medical personnel during treatment of genital warts with CO2 laser and electrocoagulation. Acta Derm Venereol 1994;74:393-5

36. Gloster Jr HM, Roenigk RK. Risk of acquiring human papillomavirus from the plume produced by the carbon dioxide laser in the treatment of warts. J Am Acad Dermatol 1995;32:436-41

37. Capizzi PJ, Clay RP, Battey MJ. Microbiologic activity in laser resurfacing plume and debris. Lasers Surg Med 1998;23:172-4

38. Hughes PS, Hughes AP. Absence of human papillomavirus DNA in the plume of erbium:YAG laser-treated warts. J Am Acad Dermatol 1998;38:426-8

39. Lobraico RV, Schifano MJ, Brader KR. A retrospective study on the hazards of the carbon dioxide laser plume. J Laser Appl 1988;1:1-8

40. Calero L, Brusis T. Laryngeal papillomatosis-first recognition in Germany as an occupational disease in an operating room nurse [article in German]. Laryngorhinootologie 2003;82:790-3

41. Ilmarinen T, Auvinen E, Hiltunen-Back E, Ranki A, Aaltonen Lm, Pitkäranta A. Transmission of human papillomavirus DNA from patient to surgical masks, gloves and oral mucosa of medical personnel during treatment of laryngeal papillomas and genital warts. Eur Arch Otorhinolaryngol 2012;269:2367-71

42. Martinelli F, Garbi A. Change in practice in gynecologic oncology during the COVID-19 pandemic: a social media survey Int J Gynecol Cancer 2020;30:1101-1107. doi:10.1136/ijgc-2020-001585

43. Centers for Disease Control and Prevention (US). Interim U.S. guidance for risk assessment and public health management of healthcare personnel with potential exposure in a healthcare setting to patients with coronavirus disease (COVID-19) [Internet]. Atlanta: CDC; 2020 [cited 2020 Mar 31]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-risk-assesment-hcp.html

44. American Association of Gynecologic Laparoscopists (AAGL). Joint statement on minimally invasive gynecologic surgery during the COVID-19 pandemic [Internet]. Cypress: AAGL; 2020 [cited 2020 Mar 31]. Available from: https://www.aagl.org/news/covid-19-joint- statement-on-minimally-invasive-gynecologicsurgery/

45. American College of Surgeons (ACS). COVID-19: elective case triage guidelines for surgical care [Internet]. Chicago: ACS; 2020 [cited 2020 Mar 31]. Available from: https://www.facs.org/covid-19/clinical-guidance/elective-case

46. British Gynaecological Cancer Society (BGCS). BGCS framework for care of patients with gynaecological cancer during the COVID-19 pandemic [Internet]. London: BGCS; 2020 [cited 2020 Mar 31]. Available from: https://www.bgcs.org.uk/wp- content/uploads/2020/03/BGCS-covid-guidance-v1.-22.03.2020.pdf

47. EAU Robotic Urology Section (ERUS). ERUS (EAU Robotic Urology Section) guidelines during COVID-19 emergency [Internet]. Arnhem: ERUS; 2020 [cited 2020 Mar 31]. Available from: https://uroweb.org/wpcontent/uploads/ERUS-guidelines-for-COVID-def.pdf

48. European Society for Gynaecological Endoscopy (ESGE). ESGE recommendations on gynaecological laparoscopic surgery during COVID-19 outbreak [Internet]. Leuven: ESGE; 2020 [cited 2020 Mar 31]. Available from: https://esge.org/wp-content/uploads/ 2020/03/Covid19StatementESGE.pdf

49. Royal College of Obstetricians and Gynaecologists (RCOG)/British Society for Gynaecological Endoscopy (BSGE). Joint RCOG/BSGE statement on gynaecological laparoscopic procedures and COVID-19 [Internet]. London: RCOG/BSGE; 2020 [cited 2020 Mar 31]. Available from: https://mk0britishsociep8d9m.kinstacdn.com/wp-content/uploads /2020/03/Joint- COG-BSGE-Statement- ongynaecological-laparoscopic - procedures-and-COVID- 19.pdf

50. Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). SAGES and EAES recommendations regarding surgical response to COVID-19 crisis [Internet]. Los Angeles: SAGES; 2020 [cited 2020 Mar 31]. Available from: https://www.sages.org/recommendations-surgical-response-covid-19/

51. Society of Gynecologic Oncology (SGO). Surgical considerations for gynecologic oncologists during the COVID-19 pandemic [Internet]. Illinois: SGO; 2020 [cited 2020 Mar 31]. Available from: https://www.sgo. org/wp- content/uploads/2020/03/Surgical_Considerations_Communique.v14.pdf