NEW CORONAVIRUS INFECTION (COVID-19) IN ADULTS: CLINICAL AND LABORATORY FEATURES
Abstract
The aim of the research was to study the dynamics of clinical, laboratory and hormonal parameters of the thyroid gland and adrenal glands in adult patients with COVID-19, depending on the severity of the disease.
Material and methods. 166 case histories of patients with a confirmed diagnosis of U07.1 Coronavirus infection (COVID-19), aged 18 to 65 years old, have been studied. Patients with moderate COVID-19 prevailed and amounted to 140 people (84.33%), severe infection was noted in 26 patients (15.66%). Patients were admitted to the hospital at different times from the moment of the disease (from the second to the 19th day of the disease), on average for 8.34±0.37 days.
Results. In patients with moderate to severe COVID-19, catarrhal respiratory syndrome, intoxication syndrome and multiple organ dysfunction prevail. In severe disease, a pronounced immune-inflammatory syndrome develops and is characterized by a significant increase in serum levels of D-dimer (505.5±171.34ng/ml), C-reactive protein (52.75±11.52mg/l), fibrinogen (4.91±0.27g/l) (p<0.05). The revealed changes in the values of thyroid and adrenal hormones in patients during acute period of moderate and severe COVID-19 do not depend on the severity of the disease. In COVID-19 convalescents, 6 months after the disease, the content of thyroid and adrenal hormones in the blood generally reaches the values of the control group (p<0.05).
About the Authors
Ya. V. Malikova
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
D. A. Valishin
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
R. T. Murzabaeva
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
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Review
For citations:
Malikova Ya.V., Valishin D.A., Murzabaeva R.T. NEW CORONAVIRUS INFECTION (COVID-19) IN ADULTS: CLINICAL AND LABORATORY FEATURES. Bashkortostan Medical Journal. 2024;19(3):29-34. (In Russ.)
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