СРАВНИТЕЛЬНАЯ ХАРАКТЕРИСТИКА ВИДОВ 3D-БИОПЕЧАТИ И ВОЗМОЖНОСТИ ИХ ПРИМЕНЕНИЯ В КЛИНИЧЕСКОЙ ПРАКТИКЕ

Дефицит тканей и органов является серьезной медицинской проблемой. Трехмерная биопечать представляет собой мультидисциплинарную технологию для проектирования трехмерных биологических тканей со сложной архитектурой и составом. Данная технология является многообещающей благодаря точному нанесению клеток пациента или донора в соконструктов для тканевой инжнерии и регенеративной медицины. Весьма привлекательным для применения в клинической практике является появление технологии in-situ биопечати. Например, данная технология представляет собой прямую печать в месте дефекта, что значительно повышает возможности ее использования в регенеративной медицине.
Цель данного обзора – провести сравнительную характеристику основных и новых стратегий 3D-биопечати. Проведён анализ публикаций и исследований, находящихся в открытом доступе, отражающем основные результаты научных работ за последние 20 лет. По результатам проведенного анализа представлены основные типы биопечати, их достоинства и недостатки, возможности их применения для создания конструктов для тканевой инженерии и регенеративной медицины.

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