PURULENT-SEPTIC COMPLICATIONS IN HIV-INFECTED PATIENTS

Abstract

The course of an acute surgical pathology at patients with HIV infection is much severe because of an immunodeficiency, the opportunistic and accompanying infections, especially at generalization of a coinfection and neoplastic processes.Research objective is identification of major pathophysiological factors influencing the results of treatment of purulent-septicstates at HIV-positive patients and searching of paths of their improvement.The research resulted in determination of decisive influence on the severity of the course of purulent - septic abdominal diseases at HIV - infected patients of such factors as the initial background including the disease duration, the HIV infection stage, effectiveness of antiretroviral therapy (ART), existence of comorbid pathology. Pyoinflammatory lesions of soft tissues at HIV infection differ in poorly expressed signs of local inflammation, therefore, it is necessary to enhance diagnostic tests with ultrasonography for specification of extensiveness and depth of lesion. Timely starting antibacterial therapy is extremely important for arresting pyoinflammatory process. At the same time it is necessary to consider nearly in all cases existence of mixed microflora.Early diagnosis of HIV infection which is systematically carried out by ART, adequate opening and a drainage of suppurativefocuses, usage of mini-invasive technologies, targent antibacterial therapy allow to improve the results of treatment of this category of patients.