COMPREHENSIVE TREATMENT AND PREVENTION OF RECURRENT BLEEDING IN PATIENTS WITH PEPTIC ULCER OF STOMACH AND DUODENUM USING PHOTODYNAMIC THERAPY

Abstract

Acute gastroduodenal ulcer bleeding is the most serious complication of gastric and duodenal ulcer. The article presents the analysis of the results of examination and treatment of 132 patients with gastric ulcer and duodenal ulcer. To evaluate the clinical efficacy of the proposed treatments 2 groups of patients were allocated: in the basic group, the complex treatment and prevention of relapse of ulcer bleeding was conducted by a combination of injectable forms of antisecretory drugs with endoscopic photodynamic therapy. Patients of the control group underwent conventional treatment, including endoscopic hemostasis, the use of oral antisecretory drugs and H. pylori therapy. Endoscopic photodynamic therapy applied photosensitizer of the second generation "Photoditazine". In the control group, the treatment was carried out by traditional means, which included endoscopic hemostasis and the use of oral antisecretory drugs. The results indicate the reduction in the number of exacerbations and recurrent bleeding in the main group of patients treated with antiulcer treatment using photodynamic therapy.