PLATELET-RICH PLASMA IN A COMPLEX TREATMENT FOR CHRONIC CORNEAL EROSIONS OF HERPES VIRUS ETIOLOGY

Abstract

The study aimed to create a stepwise method for treatment of recurrent cornea erosion syndrome associated with herpetic and cytomegalovirus infections, using a complex treatment involving platelet-rich plasma (PRP).Experimental part of the study was performed to estimate the sterility of PRP. Clinical part of the study involved 30 patientswith chronic corneal erosions of herpes virus etiology. All patients had previously unsuccessful courses of reparative therapy. As the control the condition of the patients before the beginning of PRP therapy was used. To evaluate the efficacy of treatment we used the system of counting an index of corneal lesion by sectors in points.The study demonstrated a positive effect of the method with gradual decrease of corneal lesion index. A treatment algorithm for managing patients tolerant to common reparative therapy was developed. The average index of the corneal lesion before the 2-nd step of treatment was 7,2 points. At 4 and 8 week it was 4.2 and 2.8 points respectively.Thus, the study reveals a positive effect of PRP application during corneal erosion treatment in comparison with standard methods of therapy