OPHTHALMIC MANIFESTATIONS OF NEUROSYPHILIS

Abstract

The purpose of the work is to study the features of the clinical picture, diagnosis of ophthalmic manifestations of neurosyphilis (NS).During 2008-2017 15 patients with NS were being treated in the Republican Dermatovenerological Clinic №1 in Ufa, of them 7(46.7%) in 2017.We have examined7 patients with newly diagnosed neurosyphilis (4 males, 3 females) aged 33-62. Neurosyphilis was diagnosed on the basis of a blood and cerebrospinal fluid study, a consultation of a neurologist, dermatovenerologist, ophthalmologist. In 5 patients neurosyphilis started with ophthalmic manifestations. In 2 patients (an old married couple) early asymptomatic neurosyphilis was determined by lumbar puncture after a latent syphilis.In 4 patients with meningovascular neurosyphilis damage to the organ of vision was manifested by chorioretinitis (1 case), uveitis (2 HIV-infected patients), optic neuritis (1 patient), and bilateral primary optic nerve atrophy in 1 patient with late NS. 80% of cases (8 eye) showed bilateral process, vision loss was from decimal places to light perception in 87,5 % cases (7 eyes). Increasingcases of neurosyphilis, especially its meningovascular forms with damage to the organ of vision, low-symptomatic clinical manifes-tations require further improvement of the diagnosis of this pathology.