COMORBIDITY OF BIPOLAR AFFECTIVE DISORDER AND SOMATIC PATHOLOGY: STRUCTURE AND CLINICAL IMPORTANCE

High prevalence of somatic diseases among patients with bipolar disorder requires further widening of knowledge about interaction of affective and somatic pathologiesThe aim of the research was to study the structure and clinical importance of somatic comorbidity in patients admitted to psychiatric hospital with diagnosis of bipolar affective disorder (BAD).A continuous sample of 64 patients admitted to Samara Psychiatric Hospital in 2016th year with diagnosis of BAD (F.32) was studied. 18 of them (28%) were female and 46 (72%) - male. Mean age of the patients was 45.5±12.1 years old.All the patients had comorbid somatic disorders. Each patient had from 2 to 12 somatic diagnoses, 6.2±2.98 on an average.Structure of chronic somatic disorders in patients with BAD was the following: 96% had neurological diseases, 80% had cardiological, 72% - nephrological, 52% - endocrinological, 36% - gastroenterological, 36% - pulmonological, 28% - autoimmune and allergical, 12% - oncological, 16% - other. 86% of the studied women had gynecological diseases.The most important consequence of present somatic comorbidity in patients with BAD is need for many organizational and clinical decisions in providing medical care, besides the ones aimed at psychopathology. In training doctors and ordering equipment for psychiatric hospitals, points considering the revealed comorbidity structure should be stressed. Another aspects influencing the clinical practice are: somatic disorders as a precondition for emergency conditions; somatic disorders modifying the course and prognosis in BAD and vice versa; somatic comorbidity as a contraindication to for psychopharmacotherapy and as a fact requiring special attention to interaction between the drugs prescribed for treatment of BAD and a comorbid somatic disease.

биполярное аффективное расстройство, БАР, коморбидность, коморбидная соматическая патология, стационарная психиатрическая практика, bipolar affective disorder, BAD, comorbidity, comorbid somatic disorders, psychiatric hospital treatment

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