QUANTITAVE EVALUATION OF ANTIBIOTIC SUSCEPTIBILITY IN THE TREATMENT OF PATIENTS WITH PURULENT INFECTION

Abstract

The article describes a new method for determining the sensitivity of microbes to antibiotics. The urgency of the problem is determined by the need for early prescribing in purulent diseases and postoperative complications of antibiotics effective for the identified microflora in a particular patient.To obtain a microbiological conclusion, certain time is usually required and the so-called “starting” therapy with antibiotics isusually prescribed, the latter may be ineffective at this particular infection. The proposed method allows to calculate the sensitivity of microbes of a particular species to a specific antibiotic (coefficient ka), and also using the second coefficient (kg) - to determine the proportion of microbes of a given population that is sensitive to one or another group of antibiotics. The first factor ka allows to choose the most optimal antibiotic for a particular patient, and the second kg - to designate in the clinic, a medical organization antibiotics of reserve to reduce the likelihood of antibiotic resistance.