THE RESULTS OF SURGICAL MYOCARDIAL REVASCULARIZATION IN THE EARLY PERIOD AFTER STENTING CLINICALLY-DEPENDENT ARTERY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITHOUT ST-SEGMENT ELEVATION AND MULTIVESSEL CORONARY ARTERY DISEASE

Objective: to evaluate the efficacy and safety of surgical myocardial revascularization in the early period after stenting of clinical-dependent artery (up to 90 days) with drug-coated sirolimus of the 3rd generation in patients with acute coronary syndrome without ST-segment elevation and multivessel lesion.We have conducted a retrospective analysis of the results of 2 year observation of staged treatment of patients with acute coronary syndrome without ST-segment elevation and multivessel coronary artery disease who underwent stenting clinical dependent artery for emergency indications, and then in a period of up to 90 days underwent coronary artery bypass grafting. Statistical analysisof quantitative indicators was made by calculation of mean value and standard deviation. Qualitative indicators are represented byfrequency ratio in percent. Efficacy and safety assessment was carried out according to the criteria of «non-inferiority» in comparison with the literature data of myocardial revascularization by stenting. Differences were evaluated by assessment of the value of two-sided 95% confidence interval of odds of the obtained negative events proceeding from “non-inferiority” design.Surgical myocardial revascularization in the early stages after stenting of the clinically dependent artery in patients with acute coronary syndrome without ST-segment elevation and multivessel lesion is equivalent in efficacy and safety to percutaneous coronary intervention.

острый коронарный синдром, ишемическая болезнь сердца, аортокоронарное шунтирование, коронарный стент с лекарственным покрытием, acute coronary syndrome, coronary heart disease, coronary artery bypass grafting, drug-eluting coronary stent