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ETIOPATHOGENESIS OF ENDOMETRIAL HYPERPLASTIC PROCESSES IN WOMEN OF REPRODUCTIVE AGE

Abstract

The review presents current data on various aspects of endometrial hyperplastic processes. The etiopathogenetic mechanisms of endometrial hyperplasia in women of reproductive age are systematized. Molecular genetic, proliferative-apoptotic mechanisms for the development of pathology are shown, data on the features of expression of progesterone receptors and estrogens, the role of cytokines, hormone-metabolic processes in women with obesity, the influence of inflammatory processes of the genitals, and pathological neoangiogenesis, impaired immune status are presented.

About the Authors

V. A. Kulavsky
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation


V. A. Pushkarev
ГАУЗ «Республиканский клинический онкологический диспансер»
Russian Federation


E. V. Kulavsky
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation


A. V. Pushkarev
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation


Review

For citations:


Kulavsky V.A., Pushkarev V.A., Kulavsky E.V., Pushkarev A.V. ETIOPATHOGENESIS OF ENDOMETRIAL HYPERPLASTIC PROCESSES IN WOMEN OF REPRODUCTIVE AGE. Bashkortostan Medical Journal. 2019;14(2):71-80. (In Russ.)

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ISSN 1999-6209 (Print)