FEATURES OF THE COURSE OF ARDS IN SEVERE PNEUMONIA CAUSED BY THE NEW COVID-19 CORONAVIRUS

The aim of the study was to identify the clinical features of severe viral pneumonia associated with ARDS in the new coronavirus infection COVID-19.Methods. The study design is retrospective, single-center, controlled, and non-randomized. 25 patients met the inclusion criteria. 10 were performed artificial ventilation of the lungs, three of them died. In total, the clinic received 170 patients. We comparedthe ARDS clinical picture for non-specific severe community-acquired pneumonia and the new COVID-19 coronavirus infection.Statistical processing of the research results was carried out using the program "Statistica 6.0". Results . With a comparable initial severity of the condition on the SOFA scale (3.8+0.82 and 3.4+0.3 points), patients with covid infection were characterized by initially more pronounced hypoxemia (pO2/Fio2 - 152.3+26.1 vs. 279+61) and the presence of pronounced hemocoagulation disorders and a more rare development of shock. At the same time, there were fundamental differences in the structure of multiple organ failure (primarily the absence of encephalopathy), the nature of comorbidity, and approaches to predicting the outcome of the disease.Conclusion. Severe viral pneumonia associated with ARDS and caused by COVID-19 is characterized by unique features: initially extremely low respiratory index, the presence of pronounced hemocoagulation disorders, a longer period of ventilator therapy, and difficulties in assessing the prognosis of the disease outcome

ОРДС, COVID-19, клинические особенности, ARDS, COVID-19, clinical features