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PARAMETERS OF GENERAL IMMUNITY IN PATIENTS WITH KERATOCONUS BEFORE AND AFTER PERILIMBAL INJECTION OF “ALLOPLANT” BIOMATERIAL

Abstract

Objective. To study the general immunity parameters in patients with keratoconus before and after perilimbal injection of “Alloplant” biomaterial.Material and methods. The study group included 25 patients (17 men and 8 women) with keratoconus aged 14-44. The numberof lymphocyte subpopulations and expression of membrane activation markers were studied as long as blood levels of IgG, IgA andIgM before and after perilimbal injection of “Alloplant” biomaterial.Results. Perilimbal injection of “Alloplant” biomaterial did not affect the number of t-lymphocytes and subpopulations in patients with keratoconus. Blood immunoglobulin levels were stable during the follow-up.Conclusion. Perilimbal injection of “Alloplant” biomaterial did not affect the parameters of general immunity in patients with keratoconus.

About the Authors

V. U. Galimova
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation


R. F. Shakirov
ФГБУ «Всероссийский центр глазной и пластической хирургии» Минздрава России
Russian Federation


References

1. Иммунология глазной патологии / Н.А. Пучковская [и др.]. - М.: Медицина, 1983. - 208 с

2. Mercer, J.C. Natural killer t cells: rapid responders controlling immunity and disease / J.C. Mercer, M.J. Ragin, A. August // Int J Biochem Cell Biol. - 2005. - V.37. - P. 1337-1343


Review

For citations:


Galimova V.U., Shakirov R.F. PARAMETERS OF GENERAL IMMUNITY IN PATIENTS WITH KERATOCONUS BEFORE AND AFTER PERILIMBAL INJECTION OF “ALLOPLANT” BIOMATERIAL. Bashkortostan Medical Journal. 2020;15(4):6-8. (In Russ.)

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ISSN 1999-6209 (Print)