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OXIDATIVE STATUS OF RETINA AFTER ENDOVITREAL ILLUMINATION

Abstract

The goal was to study changes in the oxidative status of blood from the central retinal vein after endovitreal illumination.Material and methods: luminol-dependent and iron-induced chemiluminescence of whole blood and blood serum from the central retinal vein of a rabbit after experimental endoillumination with an intensity of 50% and 100%.Results and discussion: we found that under the influence of endovitreal illumination there is an increase in the generation of reactive oxygen species in the blood and an increase in the antioxidant activity of blood plasma, which depends on the endoillumination intensity.Conclusion: oxidative stress can be one of the factors of the phototoxic effect of endovitreal light sources on the retina.

About the Authors

R. R. Yamgutdinov
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России; ГБУЗ РБ «Городская клиническая больница №10»
Russian Federation


K. S. Mochalov
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation


T. R. Mukhamadeev
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России; ЗАО «Оптимедсервис»
Russian Federation


References

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2. Vitreoretinal instruments: vitrectomy cutters, endoillumination and wide-angle viewing systems / P.R. Chaves de Oliveira [et al.] // International Journal of Retina and Vitreous. - 2016. - Vol. 28.-№2.- P. 1-15

3. Liochev, S.I. Reactive oxygen species and the free radical theory of aging // S.I. Liochev // Free Radic Biol Med. - 2013. - Vol. 60. - P. 1-4

4. McCannel, C.A. Advanced in endoillumination / C.A. McCannel // Retinal physician. - 2015. - Vol. 12. - P. 9-10

5. Turrens, J.F. formation of reactive oxygen species / J.F. Turrens // Journal of Physiology. - 2003. - Vol. 552. - P. 335-44


Review

For citations:


Yamgutdinov R.R., Mochalov K.S., Mukhamadeev T.R. OXIDATIVE STATUS OF RETINA AFTER ENDOVITREAL ILLUMINATION. Bashkortostan Medical Journal. 2020;15(4):57-60. (In Russ.)

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ISSN 1999-6209 (Print)