RETROSPECTIVE STUDY OF THROMBOCYTOPENIA CAUSES IN PATIENTS OF MULTI-SPECIALTY HOSPITAL

Abstract

The causes of thrombocytopenia are very diverse, one of them is using some kind of drugs (including heparin). Most of the patients (81%) with detected reduced level of platelets in blood (<100 х 109/l) didn’t get heparin. The reasons for such thrombocytopenia can be associated with the reaction to drugs of other groups (oncological patients), pathological processes related to the main disease course. Peak frequency of thrombocytopenia despite of heparin intake is found in patients of both oncological and cardiology departments.The purpose of the study is analysis of the relevance and frequency of heparin-induced thrombocytopenia (HIT) in a multispecialty hospital. The frequency of thrombocytopenia (<100 х 109/l) in patients of a multi-specialty hospital can reach 1.36%. Among 350 patients, 66 (19%) received heparins and they can be considered as potentially suffering from HIT. Most patients (62%) were treated in surgical departments. The departments with the largest number of such patients were the cardiology department (20 people per year) and the department of vascular surgery (11 people per year). Thus, the problem of HIT seems to be very important. It is necessary to attract the attention of hospital doctors to this problem for timely diagnosis and laboratory verification of HIT.