THE FIRST EXPERIENCE OF APPLICATION OF THE RADIONUCLIDE METHOD OF DIAGNOSTICS TO ASSESS THE EFFECTIVENESS OF TREATMENT IN PATIENTS WITH DIABETIC FOOT SYNDROME

Determination of perfusion of tissues of the lower extremities using radioisotope research is a promising diagnostic method that allows us to assess the state of blood flow in large and mediumsized vessels, arterioles and capillaries of the feet, shins, as well as to detect violations of venous outflow.Purpose. To evaluate the effectiveness of treatment in patients with a neuroischemic form of diabetic foot by lower limb scintigraphy.Material and methods. We analyzed 28 patients with neuroischemic form of diabetic foot by lower limb scintigraphy.Results. Comparative analysis of scintigrams showed an asymmetric pattern in the accumulation of the radiopharmaceutical in the symmetrical muscles of the lower extremities towards a decrease in the accumulation in the lower extremity with trophic ulcers. Before treatment, the quantitative indicator of impulses from the muscles of the affected leg was 446±31.3, from the healthy leg -1082±37.1. After treatment, the number of impulses from the affected and healthy limb averaged 610±32.8 and 1147±35.4, respectively. The number of impulses in the course of treatment in the affected limb increased by an average of 195±34.1, and in the healthy one by 81±29.6. The indicator of the number of RP pulses from the affected limb before treatment was significantly lower than after treatment (U = 0, p <0.001).Conclusions. Conducting radionuclide diagnostics of the lower extremities in dynamics using the radiopharmaceutical Pirfotech99mTc in patients with diabetic foot syndrome can help to evaluate the effectiveness of conservative treatment. Further research in this area is promising and will reveal the potential of this research method.

diabetic foot syndrome, lower limb scintigraphy, neuroischemic form of diabetic foot

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