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CASTLEMAN DISEASE IN THE CLINIC OF MAXILLOFACIAL SURGERY

Abstract

The article describes a case of Castleman disease in the maxillofacial region in a woman aged 51 years. A tumor-like formation of the lateral surface of the right neck without significant anxiety grew over 18 years. A histological examination of a distant neoplasm after a surgical operation made it possible to diagnose a rare pathologyangiofollicular hyperplasia of the lymph node. Angiofollicular lymph node hyperplasia was first described by Benjamin Castleman in 1954, when solitary mediastinal lymph node hyperplasia was discovered in a patient [3].E.K. Egorova claims that Castleman disease must be divided into local and generalized (multicentric) [1]. With local Castleman disease, 3 morphological variants should be distinguished: hyaline-vascular, plazma-cellular and mixed-cellular. According to her, hyaline-vascular variant is found in 48,7% of patients, plazma-cellular - in 23,7% and mixed-cellular - in 27,6%.Manifestation of Castleman disease on the face or neck is a red flag for cancer alert.

About the Authors

A. M. Suleimanov
ГБУЗ РБ «Городская клиническая больница № 21»
Russian Federation


S. V. Shchekin
ГБУЗ РБ «Городская клиническая больница № 21»
Russian Federation


M. B. Ubaidullaev
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation


References

1. Егорова, Е.К. Клинико-морфологические особенности различных вариантов болезни Кастлемана: автореф. дис. … канд. мед. наук / Е.К. Егорова. - М., 2016. - 25с

2. Меликян, А.Л., Болезнь Кастлемана (обзор литературы) / А.Л. Меликян, Е.К. Егорова // Онкогематология. - 2016. - №2. - С.819. DOI: 10.17650/1818-8346-2016-11-2-8-20

3. Федеральные клинические рекомендации по диагностике и лечению болезни Кастлемана у детей [Электронный ресурс] / А.Г. Румянцев [и др.]; Общественная организация Национальное общество детских гематологов, онкологов; ФГБУ «ФНКЦ ДГОИ им. Дмитрия Рогачева» Минздрава России. - URL: http://nodgo.org/sites/default/files.pdf (дата обращения 04.02.2021г.)


Review

For citations:


Suleimanov A.M., Shchekin S.V., Ubaidullaev M.B. CASTLEMAN DISEASE IN THE CLINIC OF MAXILLOFACIAL SURGERY. Bashkortostan Medical Journal. 2021;16(1):116-118. (In Russ.)

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ISSN 1999-6209 (Print)