PROBLEMS OF PREVENTION OF CHRONIC KIDNEY DISEASE PROGRESSION IN CHILDREN WITH CONGENITAL MALFORMATIONS OF THE URINARY SYSTEM
Abstract
The purpose of the study is optimization of treatment of children in the Republic of Bashkortostan with congenital malformations of the urinary tract based on detection of factors of chronic kidney disease (CKD) progression, their demographic and nosological structure and features of the disease course.Study design - retrospective, observational, cohort. The study included 297 patients.All malformations of the kidneys were reliable predictors of CKD progression. Factor, twice reducing CKD progression, was timely surgery. Prevention of pyelonephritis recurrence, bacteriuria elimination, blood pressure and anemia correction also play an important role. Introduction of these principles of treatment into clinical practice for obstructive uropathies in children allowed tosignificantly reduce (p=0,007) by four times (OR - 0,25) the potential of CKD progression.Thus, development of a regional register of children with malformations of the urinary system allows to unify diagnostic, therapeutic and prognostic algorithm for management of chronic kidney disease in these patients.-
About the Author
R. Z. Akhmetshin
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
References
1. Детская нефрология: руководство для врачей/ под ред. М.С. Игнатовой. - - М.: ООО «Медицинское информационное агентство», 2011. - 3-е изд., перераб. и доп. - 696 с
2. Детская инвалидность вследствие заболеваний органов мочевой системы у детей, региональные особенности / Г.А. Маковецкая [и др.] // Нефрология и диализ. - 2006. - № 8(4). - С. 359-362
3. Молчанова Е.А., Валов А.Л. Результаты формирования регистра хронической почечной недостаточности у детей в 2000-2002 гг. / Е.А. Молчанова, А.Л. Валов // Нефрология и диализ. - 2004. - № 6 (3). - С. 221-226
4. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review / AX Garg [et al.]// JAMA. - 2005. - Vol. 293. - P. 1223-1228
5. Establishing a national knowledge translation and generation network inkidney disease: the canadian kidney knowledge translation andgeneration network / B. Manns [et al.] // Can J Kidney Health Dis. - 2014. - Vol. 1(1). - P. 2
6. The Canadian Society of Nephrology methods in developing and adapting clinical practice / R.A. Mustafa [et al.] // Canadian Journal of Kidney Health and Disease. - 2014. - Vol. P. 1-5
7. National Kidney Foundation Clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. K/DOQI clinical practice guidelines // Am J Kidney Dis. - 2002. - Vol. 39. - 266 p
8. National Kidney Foundation Clinical practice guidelines for bone metabolism and disease in children with chronic kidney disease. National Kidney Foundation KDOQI Kidney Disease Outcomes quality initiative // Am J Kidney Dis. - 2005. - Vol. 46 (4) Suppl. 1. - P. 8-121
9. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents // Pediatrics. - 2004. - Vol. 114. - P. 555-576
10. Using an electronic selfmanagement tool to support patients with chronic kidney disease(CKDD): A CKD Clinic Self-Care Model / S. Ong [et al.] //Semin Dial - 2013. - Vol. 26. - P. 195
11. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine / G.J. Schwartz [et al.] // Pediatrics. - 1976. - Vol. 58. - P. 259-263
12. Schröder C.H. European Pediatric Peritoneal Dialysis Working Group. The management of anemia in pediatric peritoneal dialysis patients. Guidelines by an ad hoc European Committee / C.H. Schröder // Pediatr Nephrol. - 2003. - Vol. 18. - P. 805-809
13. Estimating prevalence of CKD stages 3-5 using health system data / VB Shahinian [et al.] // Am J Kidney Dis. - 2013. - Vol. 61(6). - P. 930-938
14. Somu, S. Early Detection of Hypertension in General Practice / S. Somu, B. Sundaram, A.N. Kamalanathan // Archives of Disease in Childhood. - 2003. - Vol. 88. - P. 302
Review
For citations:
Akhmetshin R.Z. PROBLEMS OF PREVENTION OF CHRONIC KIDNEY DISEASE PROGRESSION IN CHILDREN WITH CONGENITAL MALFORMATIONS OF THE URINARY SYSTEM. Bashkortostan Medical Journal. 2017;12(3):6-13. (In Russ.)
Views:
78
Email this article 
