LATENCY OF THE N75 COMPONENT OF PATTERN-REVERSAL VISUAL EVOKED POTENTIALS IN THE PROGNOSIS AND ASSESSMENTOF THE EFFECTIVENESS OF AMBLYOPIA TREATMENT

Abstract

Purpose: to assess the possibility of using the latency of the N75 component of pattern-reversal visual evoked potentials (VEP)for predicting the effect of treating amblyopia in children.Material and methods. The study included 20 children between ages 3 and 15 with amblyopia. The analysis of the latency of the N75 VEP component recorded under standard conditions was carried out. Registration of VEP was carried out before and after apparatus treatment. Sequential series of checkboard patterns with a check size of 240’, 96’, 48’, 24’ and 12’ was used as a stimulus. For the treatment of patients, the devices «Ambliokor», «Ambliother», «Speckle-M» were used.Results and discussion. In the course of therapeutic measures, a statistically significant decrease in the latency of the N75 component of VEP was observed, which was most pronounced upon stimulation with high spatial frequencies. It was found that the registration and analysis of the latency of the N75 VEP for a checkboard pattern with a check size of 12´ and 24´ are effective for the prognosis and assessment of the effectiveness of treatment of amblyopia.Conclusions. The data obtained confirm the effectiveness of using the latency of the N75 component of VEP registration as a reliable method for predicting and evaluating the effectiveness of hardware-based treatment of amblyopia in children.