SPECIFIC FEATURES OF THE PATIENT’S IMMUNE STATUS WITH NON-PROLIFERATIVE DIABETIC RETINOPATHY AFTER COVID-19

Abstract

Purpose: to study general clinical and immunological parameters in a patient with diabetic nonproliferative retinopathy afterCOVID-19.Material and methods. A comprehensive examination of the patient has been carried out, including the use of general clinical and immunological methods of laboratory diagnostics.Results and discussion. The complex of laboratory studies has been carried out which showed the activation of cytotoxic reactions of the cellular and humoral immunity, representing the risk of the development and exacerbation of the autoimmune process.In order to prevent the development of pathological autoimmune manifestations in the choroid and retina, the patient underwent intravitreal injection of the angiogenesis inhibitor Lucentis in combination with the Alloplant biomaterial for therapeutic retroscleroplasty. After the surgery, the patient's visual functions have been improved.Conclusions. The obtained results indicate that early diagnosis of impaired immune functions makes it possible to choose the appropriate surgical and therapeutic methods of treatment aimed at preventing the development of the autoimmune process.