Preview

Bashkortostan Medical Journal

Advanced search

FEATURES OF THE LESION OF THE GASTROINTESTINAL TRACT IN PATIENTS WITH THE NEW CORONAVIRUS INFECTION COVID-19

Abstract

The aim of this study is to improve the quality of care for patients with new coronavirus infection (CV-19). The main objective of the study is to study the characteristics of lesions of the gastrointestinal tract (g.t.) in CV-19.Materials and methods: 237 patients with CV-19 and gastrointestinal involvement were examined. Average age was 67.6±15.0,Me = 70.5; Q25-75 = 60.0-80.0, men - 61.1%, women - 38.9%. Mortality was 46.3% and depended on the age of the patients (age r=0.3; p = 0.003). Mathematical processing of the results was performed using the STATA12. 1 package of applied statistical programs. Statistical concepts were used: «mean value», «standard deviation», medians (Me) corresponding to the 10th and 90th percentiles (P10-P90), Pearson's χ2 criterion, t-criterion for unrelated groups. Statistical significance criterion the probability of a random error is less than 5% (P<0.05).Results. In patients with CV-19, in 70.0% of cases, the distal section from the dome of the cecum to the rectum is affected. Themain clinical manifestations of gastrointestinal lesions are bleeding - 87.5%, while no gross abnormalities in the coagulogram were revealed. The average age of patients with lesions of the upper sections (u.s.) 68.1±15.4 Me = 71.5; Q25-75 = 61.5 - 81.0, lower sections (l.s): 66.6±14.5, Me = 68.0; Q25-75 = 69.5-79.0. In terms of gender, men predominate in the void-72.2%, in the women -61.1%. Mortality in case of u.s. lesion. - 56.9%, l.s. - 25.0%.Conclusions. Questions about the damage to the digestive system in CV-19 remain poorly understood and require further research.

About the Authors

E. V. Fedotova
ГБУЗ Архангельской области «Северодвинская ГКБ №2»; ФГБОУ ВО «Северный государственный медицинский университет» Минздрава России
Russian Federation


S. M. Dynkov
ФГБОУ ВО «Северный государственный медицинский университет» Минздрава России
Russian Federation


V. V. Netsvetaev
ГБУЗ Архангельской области «Северодвинская ГКБ №2»
Russian Federation


References

1. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 3: Временные методические рекомендации. - М., 2020. - 63 с

2. Новая коронавирусная инфекция (COVID-19) и система органов пищеварения / В.Т. Ивашкин [и др.] // Российский журнал гастроэнтерологии, гепатологии, колопроктологии - 2020. - Т. 30, №3. - С. 7-13

3. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 13: Временные методические рекомендации. - М., 2021. - 237 с

4. Diarrhoea may be underestimated: a missing link in 2019 novel coronavirus / W. Liang [et al.] // Gut. - 2020. - Vol. 69, N 6. - Р.1141- 1143. https://doi.org/10.1136/gutjnl-2020-320832

5. Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study / L. Pan [et al.] // Am. J. Gastroenterol. - 2020. - Vol. 115, N 5. - Р.766-773. https://doi.org/10.14309/ajg.0000000000000620

6. Prise en charge des hémorragies digestives basses graves [electronic resource] / S. Nahon [et al.] // Acta Endoscopica. - 2014. - Vol. 44. - P. 98-108.doi:10.1007/s10190-013-0341-1


Review

For citations:


Fedotova E.V., Dynkov S.M., Netsvetaev V.V. FEATURES OF THE LESION OF THE GASTROINTESTINAL TRACT IN PATIENTS WITH THE NEW CORONAVIRUS INFECTION COVID-19. Bashkortostan Medical Journal. 2021;16(5):5-9. (In Russ.)

Views: 97


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1999-6209 (Print)