FEATURES OF THE LESION OF THE GASTROINTESTINAL TRACT IN PATIENTS WITH THE NEW CORONAVIRUS INFECTION COVID-19
Abstract
The aim of this study is to improve the quality of care for patients with new coronavirus infection (CV-19). The main objective of the study is to study the characteristics of lesions of the gastrointestinal tract (g.t.) in CV-19.Materials and methods: 237 patients with CV-19 and gastrointestinal involvement were examined. Average age was 67.6±15.0,Me = 70.5; Q25-75 = 60.0-80.0, men - 61.1%, women - 38.9%. Mortality was 46.3% and depended on the age of the patients (age r=0.3; p = 0.003). Mathematical processing of the results was performed using the STATA12. 1 package of applied statistical programs. Statistical concepts were used: «mean value», «standard deviation», medians (Me) corresponding to the 10th and 90th percentiles (P10-P90), Pearson's χ2 criterion, t-criterion for unrelated groups. Statistical significance criterion the probability of a random error is less than 5% (P<0.05).Results. In patients with CV-19, in 70.0% of cases, the distal section from the dome of the cecum to the rectum is affected. Themain clinical manifestations of gastrointestinal lesions are bleeding - 87.5%, while no gross abnormalities in the coagulogram were revealed. The average age of patients with lesions of the upper sections (u.s.) 68.1±15.4 Me = 71.5; Q25-75 = 61.5 - 81.0, lower sections (l.s): 66.6±14.5, Me = 68.0; Q25-75 = 69.5-79.0. In terms of gender, men predominate in the void-72.2%, in the women -61.1%. Mortality in case of u.s. lesion. - 56.9%, l.s. - 25.0%.Conclusions. Questions about the damage to the digestive system in CV-19 remain poorly understood and require further research.
About the Authors
E. V. Fedotova
ГБУЗ Архангельской области «Северодвинская ГКБ №2»; ФГБОУ ВО «Северный государственный медицинский университет» Минздрава России
Россия
S. M. Dynkov
ФГБОУ ВО «Северный государственный медицинский университет» Минздрава России
Россия
V. V. Netsvetaev
ГБУЗ Архангельской области «Северодвинская ГКБ №2»
Россия
References
1. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 3: Временные методические рекомендации. - М., 2020. - 63 с
2. Новая коронавирусная инфекция (COVID-19) и система органов пищеварения / В.Т. Ивашкин [и др.] // Российский журнал гастроэнтерологии, гепатологии, колопроктологии - 2020. - Т. 30, №3. - С. 7-13
3. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 13: Временные методические рекомендации. - М., 2021. - 237 с
4. Diarrhoea may be underestimated: a missing link in 2019 novel coronavirus / W. Liang [et al.] // Gut. - 2020. - Vol. 69, N 6. - Р.1141- 1143. https://doi.org/10.1136/gutjnl-2020-320832
5. Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study / L. Pan [et al.] // Am. J. Gastroenterol. - 2020. - Vol. 115, N 5. - Р.766-773. https://doi.org/10.14309/ajg.0000000000000620
6. Prise en charge des hémorragies digestives basses graves [electronic resource] / S. Nahon [et al.] // Acta Endoscopica. - 2014. - Vol. 44. - P. 98-108.doi:10.1007/s10190-013-0341-1
For citations:
Fedotova E.V.,
Dynkov S.M.,
Netsvetaev V.V.
FEATURES OF THE LESION OF THE GASTROINTESTINAL TRACT IN PATIENTS WITH THE NEW CORONAVIRUS INFECTION COVID-19. Bashkortostan Medical Journal. 2021;16(5):5-9.
(In Russ.)
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