EARLY RESULTS OF SURGICAL TREATMENT OF ACUTE POSTOPERATIVE ENDOPHTHALMITIS USING RECOMBINANT PROUROKINASE
Abstract
Objective. To evaluate the effectiveness of surgical treatment of acute postoperative endophthalmitis using recombinant prourokinase.
Material and methods. The study involved 5 patients from a case series of acute endophthalmitis after cataract surgery. In all patients, signs of endophthalmitis appeared 3-4 days after surgery. All patients underwent microinvasive subtotal vitrectomy on the day of referring without inducing posterior detachment of the hyaloid membrane with intravitreal injection at the end of the operation of a combination of an antibiotic and recombinant prourokinase.
Results. On the first day after surgery, all patients had severe inflammatory manifestations, which completely disappeared on the 7th day. Maximum corrected visual acuity (MCVA) after 1 month was: 0.7 in 1 patient, 0.8 in 1 patient, 1.0 in 3 patients.
Conclusion. The use of recombinant prourokinase in combination with intravitreal antibiotics and vitrectomy demonstrated good results in relieving the inflammatory process with high functional indicators according to MCVA and the absence of postoperative complications during follow-up periods of up to 1 month.
About the Authors
D. V. Petrachkov
ФГБНУ «НИИ Глазных болезней им. М.М. Краснова»
Russian Federation
Russian Federation
E. N. Korobov
ФГБНУ «НИИ Глазных болезней им. М.М. Краснова»
Russian Federation
Russian Federation
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Review
For citations:
Petrachkov D.V., Korobov E.N. EARLY RESULTS OF SURGICAL TREATMENT OF ACUTE POSTOPERATIVE ENDOPHTHALMITIS USING RECOMBINANT PROUROKINASE. Bashkortostan Medical Journal. 2024;19(2):89-93. (In Russ.)
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