PROBLEMS OF ANTIBACTERIAL THERAPY IN OUTPATIENT PEDIATRIC PRACTICE
Abstract
Worldwide, one of the most important problems in therapy with systemic antimicrobials is antimicrobial resistance. In addition, when prescribing antibacterial therapy to pediatric patients, it is necessary to pay special attention to the selection of the optimal dosage and dosage regimen.
The purpose of this work was to assess the rationality of prescribing antibacterial drugs in outpatient pediatric practice.
Materials and methods. To conduct the study, a methodology was developed that included a structural analysis of drug prescriptions in outpatient pediatric practice, identifying cases of off-label prescriptions of antibacterial drugs and formulating proposals for rational use.
Results. It was found that of the prescribed systemic antibacterial drugs, the combination of amoxicillin with clavulanic acid was most often prescribed (56.3% of the number of prescriptions in group J01). None of the prescribed drugs in this group has “children’s” status. Of the total number of prescriptions for drugs from group J01, 14.0% were classified as off-label. Thus, despite the wide range of antibacterial drugs currently available on the pharmaceutical market, there are cases of these drugs being prescribed outside the instructions.
About the Authors
L. I. Sotnikova
ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы»
Russian Federation
Russian Federation
E. E. Loskutova
ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы»
Russian Federation
Russian Federation
M. M. Kurashov
ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы»
Russian Federation
Russian Federation
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Review
For citations:
Sotnikova L.I., Loskutova E.E., Kurashov M.M. PROBLEMS OF ANTIBACTERIAL THERAPY IN OUTPATIENT PEDIATRIC PRACTICE. Bashkortostan Medical Journal. 2024;19(1):45-48. (In Russ.)
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