PATHOMORPHOLOGICAL CHARACTERISTICS OF MYOCARDIAL INFARCTION DEVELOPED ON THE BACKGROUND OF COVID-19

Objective. To evaluate the pathomorphological features of heart tissue changes in patients with acute myocardial infarction that developed against the background of COVID-19 coronavirus infection.

Material and methods. The work is based on the results of the analysis of 281 protocols of pathoanatomical autopsies of COVID-19 patients conducted at the pathoanatomical department of City Clinical Hospital №6 (Izhevsk) in the period from January to December 2022.

Results. In persons who died from coronavirus infection and its complications, acute myocardial infarction (AMI) occurs in 33.1% of cases. In 58.1%, signs of AMI were determined macroscopically at autopsy, in 41.9% – on the basis of histological examination (microinfarction was diagnosed). AMI in patients with COVID-19 develops against the background of thromboembolic events and generalized thrombohemorrhagic syndrome. Interstitial myocarditis develops in patients with small-focal infarction in 12.8% of cases against the background of bacterial pneumonia and sepsis.

Conclusion. Small-focal myocardial infarction in patients with COVID-19 poses difficulties for intravital diagnosis. Microinfarction in patients with coronavirus infection may be accompanied by interstitial myocarditis.

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