Structural features of the pineal body of experimental animals at immunotropic exposure
Abstract
The aim of the study was to investigate the structural features of the pineal body of experimental animals during immunostimulation.
Material and methods. The study was carried out on 60 mature rats after administration of imunofan. The rats were excised after administration of the drug after 1, 7, 15, 30 and 60 days. The features of the organometric and micromorphometric parameters of the pineal gland were studied.
The results obtained indicate an active response of the pineal gland to immunostimulation. The injection of an immunostimulator led to a statistically significant increase in the morphometric parameters of the pineal gland at late stages of observation at both the organ and light-optical levels of study, which may indicate a systemic reaction of the organ to immunotropic effects.
About the Authors
A. A. Bolgarova
ФГБОУ ВО «Луганский государственный медицинский университет имени Святителя Луки» Минздрава России
Russian Federation
Russian Federation
A. A. Zakharov
ФГБОУ ВО «Луганский государственный медицинский университет имени Святителя Луки» Минздрава России
Russian Federation
Russian Federation
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Review
For citations:
Bolgarova A.A., Zakharov A.A. Structural features of the pineal body of experimental animals at immunotropic exposure. Bashkortostan Medical Journal. 2024;19(4):41-44. (In Russ.)
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