Affective disordes in patients with amyotrophic lateral sclerosis
Abstract
The aim. To study affective disorders in patients with amyotrophic lateral sclerosis (ALS).
Material and methods. Fifty patients with ALS were investigated using ALSFRS-R (ALS Functional Rating Scale), Kings College staging system, Patient Health Questionnaire (PHQ-9) and The Generalized Anxiety Disorder 7 scale (GAD-7). Methods of non-parametric statistics were used for the analysis.
Results. Symptoms of clinically significant depression were registered in 42 out of 50 (84%) patients. Anxiety disorders were identified in 13 (26%) patients with ALS. Comparative analysis did not reveal significant difference in the severity of depression and anxiety in patients with ALS depending on sex, form and stage of the disease (p>0,05).
Conclusion. The results of the study confirmed high frequency of affective disorders in ALS. This needs to be taken into account while planning measures of palliative care.
About the Authors
D. K. Areprintseva
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
L. A. Smakova
Институт биохимии и генетики ФГБНУ «Уфимский федеральный исследовательский центр Российской академии наук»
Russian Federation
Russian Federation
M. A. Kutlubaev
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
E. V. Pervushina
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
I. M. Khidiyatova
Институт биохимии и генетики ФГБНУ «Уфимский федеральный исследовательский центр Российской академии наук»
Russian Federation
Russian Federation
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Review
For citations:
Areprintseva D.K., Smakova L.A., Kutlubaev M.A., Pervushina E.V., Khidiyatova I.M. Affective disordes in patients with amyotrophic lateral sclerosis. Bashkortostan Medical Journal. 2024;19(4):63-65. (In Russ.)
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