Preview

Bashkortostan Medical Journal

Advanced search

ANATOMIC FEATURES OF THE EYEBALL AND ORBIT IN HUMAN PRENATAL ONTOGENESIS

Abstract

Obtaining qualitative and quantitative data on the anatomy of the eyeball and orbit in a second-trimester fetus is the basis for developing surgical methods for correcting anomalies in utero.

Objective. To identify the features of the anatomy of the eyeball and orbit in human prenatal ontogenesis.

Material and methods. The study was conducted on a complex of anatomical structures «eyeball orbit» of 100 human fetuses of the second trimester of both sexes using morphological methods (classical anatomical study) and the method of intravital visualization.

Results. The eyeball is formed in the second trimester, its size averages from 8.36 ± 2.01 mm to 8.85 ± 2.37 mm. In a secondtrimester fetus, the eyeball consists of three membranes (fibrous, vascular and internal), the ratio of their thickness by the end of the second trimester is 53%, 25%, 22%, respectively. One of the features of fetal development is a change in the position of the eyeball in the orbit.

Conclusion. The features of the development of the anatomy of the eyeball and orbit in the second trimester have practical significance for the manifestation of feto-anomalous alertness and contribute to the development of microsurgical techniques.

About the Authors

S. I. Naydenova
Оренбургский филиал ФГАУ НИМЦ МНТК «Микрохирургия глаза им. акад. С.Н. Федорова» Минздрава России
Russian Federation


E. D. Lutsai
ФГБОУ ВО «Оренбургский государственный медицинский университет» Минздрава России
Russian Federation


I. V. Astafyev
ФГБОУ ВО «Оренбургский государственный медицинский университет» Минздрава России
Russian Federation


A. A. Grigorieva
ФГБОУ ВО «Оренбургский государственный медицинский университет» Минздрава России
Russian Federation


References

1. Imangalieva Н., Nurlanova Г., Isenova С., Apselenova М., Dadaeva Л. and Urkenova А. Modern aspects of intrauterine correction of fetus developmental defects: А literature review. Reproductive Medicine (Central Asia). 2024;1:103–112. (in Russ) DOI:https://doi.org/10.37800/RM.1.2024.103-112.

2. Bulatova, V. V., Gusarova E. O. 10 years since the first operation in chelyabinsk for twin-to-twin transfusion syndrome. Bulletin of operative surgery and topographic anatomy. 2023;1(1(8)):4-7. (in Russ).

3. Neprokina A.V., Lutsai E.D. Topographic and anatomical relationships of the lower jaw and auricle in human prenatal ontogenesis. Science and Innovations in Medicine. 2023;8(1):13-16. doi: 10.35693/2500-1388-2023-8-1-13-16 (in Russ).

4. Kozlov Yu.A., Kosovtseva N.V., Bashmakova N.V., Malgina G.B., Rasputin A.A., Kovalkov K.A. Fetoscopic repair of myelomeningocele – first russian experience. Pediatria n.a. G.N. Speransky. 2022; 101 (1): 218-225.DOI 10.24110/0031-403X-2022-101-1-218-225. (in Russ).

5. Kosovtsova NV, Pospelova YaYu, Pavlichenko MV, Markova TV, Osipova LE, Fedorova NA. Non-immune fetal hydrops. Technologies of intrauterine correction. Russian Bulletin of Obstetrician-Gynecologist. 2024;24(2):97-103. (In Russ.) https://doi.org/10.17116/rosakush20242402197

6. Neonatal'naya oftal'mologiya: rukovodstvo dlya vrachej (Neonatal ophthalmology: a guide for doctors): pod redakciej V. V. Brzheskogo, D. O. Ivanova. Moskva: GEOTAR-Media, 2021:288. (in Russ).

7. Yanin V.L., Solov'ev G. S., Ugleva T. N. [et al.] The structure of the nephrons of the kidneys of premature infants with extremely and very low body weight, born as a result of very early preterm birth at the post-conceptual age. The scientific and practical journal of medicine. 2020;4(26):24-33. – DOI 10.25017/2306-1367-2020-26-4-24-33. (in Russ).

8. Koshic I.N., Svetlova O.V. Ontogenez formirovaniya neobhodimoj dliny glaza i metabolicheskaya teoriya patogeneza miopii (Ontogenesis of the formation of the required eye length and the metabolic theory of the pathogenesis of myopia). Biomekhanika glaza–2007: sbornik trudov konferencii. Moskva, 2007:13-33. (in Russ).

9. Vasil'ev A. V., Egorov V. V., Smolyakova G. P. Anatomic-physiological parameters of children's eyes with congenital cataract were underwent cataract surgery by the method of aspiration with iol implantation on the first year of life: part 1. The dynamics of anatomical and optical parameters of pseudophakic eyes. Refraktsionnaya khirurgiya i oftal'mologiya. 2010;10(3):27–34. (in Russ).

10. Schaeffel F. Prevention of myopia. Ophthalmology. 2019;116(6):509-517. (in Engl) DOI: 10.1007/s00347-0190892-4.

11. Verma A. A novel review of the evidence linking myopia and high intelligenc. Ophthalmology. 2015; Article ID 271746:1-8. (in Engl) URL: hindawi.com/journals/joph/2015/271746.

12. Reva G. V. [et al.] Prenatal horioidal angiogenesis. Fundamental research. 2013;7–1:158–164. (in Russ).

13. Kagan I. I., Kanyukov V. N. Klinicheskaya anatomiya organa zreniya (Clinical anatomy of the organ of vision). Orenburgskaya gosudarstvennaya medicinskaya akademiya, Orenburgskij filial gosudarstvennogo uchrezhdeniya MNTK «Mikrohirurgiya glaza». SanktPeterburg: Eskulap, 2014:191. (in Russ).

14. Amosov V.I., D.V. Voronin, M.N. Korlyakova. New approaches to expert prenatal ultrasound diagnosis of eye hypotelorism and hypertelorism. Russian ophthalmological journal. 2011;4(1):4-9. (in Russ).

15. Sennikova J.V., Zheleznov L.M. Some parameters of the facial skull of the human fetus in the 14-17 weeks of fetal development. Journal of Anatomy and Histopathology. 2015;4(3):110-110. (In Russ.) https://doi.org/10.18499/2225-7357-2015-4-3-110-110


Review

For citations:


Naydenova S.I., Lutsai E.D., Astafyev I.V., Grigorieva A.A. ANATOMIC FEATURES OF THE EYEBALL AND ORBIT IN HUMAN PRENATAL ONTOGENESIS. Bashkortostan Medical Journal. 2025;20(3):46-50. (In Russ.)

Views: 11


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1999-6209 (Print)