THE STUDY OF THE CONDITIONS FOR OBTAINING THE EXTRACT FROM HERB OF THLASPI ARVENSE L.
Abstract
The purpose of the study. The study of conditions for obtaining a dry extract from herb of Thlaspi arvense L.
Material and methods. The herb of Thlaspi arvense L. harvested in the Republic of Bashkortostan was used as an object of research. The selection of optimal parameters for the extraction of the amount of biologically active substances from the herb of the Thlaspi arvense L was carried out using a pharmacopoeial method for the quantitative determination of extractive substances (single extraction).
Results. During the study, the most effective conditions for the extraction of biologically active substances from the herb of the Thlaspi arvense L. were determined. For maximum efficiency of extraction of the target components, it is recommended to use: extractant 70% ethyl alcohol; the optimal particle size of the raw material should be 2 mm; the ratio of solid (raw material) and liquid (extractant) phases – 1:50; the system reaches an equilibrium state at a temperature of 80-90°C 60 minutes after the first phase contact and within 30 minutes after two subsequent contacts. As a result, triple extraction is optimal, in which it is possible to extract the main components by 80-90% of the original.
Conclusions. Based on the conducted research, a method has been proposed for obtaining a dry extract from the herb of the Thlaspi arvense L. using 70% ethyl alcohol as an extractant. The data obtained are the basis for further development of a rational dosage form from the herb of the Thlaspi arvense L., as a promising source of valuable biologically active substances, and subsequent possible introduction into the practice of official medicine.
About the Authors
К. A. Pupykina
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
E. F. Koroleva
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
B. R. Khamidullin
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
D. V. Yunusov
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
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Review
For citations:
Pupykina К.A., Koroleva E.F., Khamidullin B.R., Yunusov D.V. THE STUDY OF THE CONDITIONS FOR OBTAINING THE EXTRACT FROM HERB OF THLASPI ARVENSE L. Bashkortostan Medical Journal. 2025;20(3):69-72. (In Russ.)
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