PREDICTION OF RESTENOSIS IN THE CORONARY STENT AT THE ACUTE CORONARY SYNDROME

Abstract

Instrumental studies were conducted to predict restenosis in the coronary stent at the acute coronary syndrome. The study included 4028 patients with acute coronary syndrome receiving inpatient treatment in Republican Cardiology Center of Ufa in the period from 2003 to 2017. To improve the long-term results of percutaneous coronary interventions, it is necessary to identify the predictors involved in the pathophysiology of restenosis in the coronary stent. Research methods included biophysical (ECG, Holter-ECG, Holter-AD, intravascular ultrasound, optical coherence tomography, MRI, MSCT, coronary angiography, echocardiography) investigations. Laboratory indices of heart failure, destruction of cardiomyocytes (myoglobin, CPK-MB, and Troponin T) of the coagulation and anticoagulation system of the blood (fibrinogen, INR, APTT). The analysis of the obtained data showed that restenosis in the coronary stent most often developed in men of the older age group, who had single long, narrow stents. The most significant parameters for the prediction model of restenosis development in the coronary stent in the late postoperative period after emergency stenting of coronary vessels are the number and diameter of the stents with the highest sensitivity and specificity, as well as such parameters of echocardiography as the final systolic size of the left ventricle and the diameter of the ascending part of the aorta.