FEATURES OF ETIOLOGICAL STRUCTURE AND ANTIMICROBIAL RESISTANCE IN COMMUNITY-ACQUIRED PNEUMONIA UNDER THE CONDITIONS OF UFA CITY HOSPITAL

Abstract

Purpose of the study: to determine the current etiological structure of community-acquired pneumonia (CAP) taking into account the sensitivity of pathogens to antimicrobial agents (AMP) in patients with community-acquired pneumonia in a city hospital in Ufa.Material and methods: A total of 196 patients hospitalized in the City Clinical Hospital No. 5 of Ufa were examined for CAPduring the period from January to December 2019, aged 18 to 90 years old. Patients were examined and treated in accordance with Federal clinical recommendations for CAP of 2018. Sputum was taken for bacteriological studies and to determine the sensitivity of microorganisms to AMP with following scientific and statistical analysis of the results. Results and conclusions: the most frequent causative agents of CAP in 2019 in the City Clinical Hospital No. 5 of Ufa were gram-positive bacteria, mainly streptococci, with a predominance of S.haemolyticus (34.6%) and a decrease in the significant role of pneumococcus (up to 5%). β-lactam antibiotics still retain effectiveness against major pneumopathogens. To reduce the likelihood of the formation of antibiotic resistance to cephalosporins, which are most often prescribed in hospitals for the treatment of CAP, it is possible to more widely use AMPs of other classes that retain their effectiveness.