ИСПОЛЬЗОВАНИЕ КОНТРАСТНЫХ СРЕДСТВ И ПУНКЦИОННЫХ МЕТОДИК ПОД КОНТРОЛЕМ УЛЬТРАЗВУКА ДЛЯ ДИАГНОСТИКИОДИНОЧНЫХ УЗЛОВЫХ ОБРАЗОВАНИЙ ПАПИЛЛЯРНОЙ КАРЦИНОМЫ НА РАННЕЙ СТАДИИ

Ultrasound with contrast amplification (contrast echography) using sulfur hexafluoride (sulphur hexafluoride) by CEUS is an intensively developing method of medical imaging. The similarity of the echographic picture of follicular tumors, nodular form of Hashimoto's thyroiditis, even against the background of contrast enhancement with malignant lesions, makes it difficult to diagnose. Such dubious cases need to be verified. The search for specific criteria for markers in the diagnosis of early forms of thyroid cancer allows to make a timely diagnosis, optimally select the area of interest for sampling, differentiate doubtful cases, and adopt reasonable treatment tactics. Detection of low-speed blood flow (microcirculation) in nodular formations of carcinoma, allows us to understand the angiogenesis of the tumor in more detail.The purpose of the study is to find specific criteria for markers in the diagnosis of early forms of thyroid cancer, to improve the effectiveness in the diagnosis of doubtful cases.Material and methods. The analysis of characteristic ultrasound signs against the background of sulfur hexafluoride (sulphurhexafluoride) by CEUS in 400 patients was performed. The group included patients with single nodular formations corresponding to the T1 C73 stage. In women, T1-sized formations accounted for 379 patients, and in men, T1-sized formations accounted for 21 patients. The average amount of formations with stage T1a in women amounted to 0,05 cm3 (CC), men - a 0.05 cm3; and stage T1b in women was 0.32 per CC in men and 0.8 CC. Among the studied patients, 379 (94.75%) were women and 21 (5.25%) - men. The mean age was 60 years.Results. Sensitivity = 99,1%, specificity = 100%, diagnostic accuracy of the method = 99,5%.Conclusions. The conducted studies clearly show not only differences in the contrast pattern of benign and malignant formations, but also the presence of a characteristic contrast defect for malignant formations in the form of an avascular zone in the arterial phase.

thyroid cancer, ultrasound diagnostics, cancer diagnostics, Oncology, CEUS method

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