GASTROENTEROLOGICAL MANIFESTATIONS OF A NEW CORONAVIRUS INFECTION (COVID-19) UPON ADMISSION TO THE HOSPITAL OF PATIENTS OF MILD AND MODERATE SEVERITY

Abstract

Purpose.To study the features of clinical manifestations of the treatment of a new coronavirus infection (COVID-19) in patients of mild and moderate severity at the stage of hospitalization, paying special attention to changes in the gastrointestinal tract (gastrointestinal tract).Material and methods. The gastroenterological manifestations of the new coronavirus infection (COVID-19) were previouslyretrospectively studied in 1180 patients, a questionnaire and a study design were compiled, which included 80 patients, whose average age was 45 years, hospitalized with a confirmed diagnosis of COVID-19, 19 of them had mild and 61 - moderate severity of the disease. The scope of the examination included questionnaires, traditional clinical, clinical and laboratory, biochemical, instrumental and radiation studies, as well as unique methods for studying microbiota and intestinal permeability.Results. The features of the course of COVID-19 at the stage of admission to the hospital were studied, the most significant clinical manifestations of the disease, including from the gastrointestinal tract, were identified. Thus, the presence of dyspeptic syndrome was detected in 83.8% of patients, diarrhea - in 37.5%, heartburn - in 27.5%, abdominal pain syndrome - 45% of patients. The development of gastroenterological manifestations of COVID-19 was combined with a more severe course of the disease and required the development of individual approaches to their correction.