DDD-ANALYSIS OF ANTIMICROBIAL CONSUMPTION IN SURGICAL DEPARTMENT OF THE MULTIPROFILE HOSPITAL OF THE REPUBLIC OF TAJIKISTAN

Abstract

One of the most important directions of pharmacoepidemiological studies is the analysis of the consumption of antimicrobial drugs. This is due to the formation of resistance of pathogenic microorganisms with the wide use of drugs of this group in the region, the country and the world as a whole.The aim of the work was to study the frequency, pattern of consumption of antibacterial drugs in the surgical departments of the multiprofile hospital of the Republic of Tajikistan, to identify the most frequently consumed and most expensive antibacterial drugs.Material and methods. The pharmacoepidemiological analysis was carried out using the recommended ATC / DDD methodology by the World Health Organization.Results. The pharmacoepidemiological analysis of the consumption of antimicrobial drugs in the surgical departments of the multiprofile hospital showed that in 8 years there has been a significant increase in the level of consumption and at the same time asignificant change in the structure of consumption of antimicrobial agents in surgical pathology. There is a clear trend towards thetransition to antimicrobials of the group of cephalosporins and, in particular, ceftriaxone. At the same time, the general level of consumption of antimicrobials from the group of penicillins and partially fluoroquinolones has been reduced. During the whole study period, the highest level of consumption of antimicrobial drugs was noted in the department of urology and the otolaryngology department, the minimum in the therapeutic departments.Conclusion. The analysis of the consumption of antimicrobial drugs in the departments of the multiprofile hospital showed that the evaluation of DDD-indicators of drug consumption allows to change and bring into line with the department profile the quantity and range of the drugs used, and also to optimize expenses under the article "Medicaments".