FEATURES OF HEMODYNAMIC DISORDERS IN ATROPHIC FORM OF CHRONIC ENDOMETRITIS
Abstract
Purpose: to identify the features of hemodynamic disorders in women with atrophic form of chronic endometritis (CE).Material and methods. 86 patients took part, who were divided into two groups: group 1 - 44 patients with CE and hemodynamic disorders in the endometrium, group 2 - 42 patients with CE without impaired microcirculation in the endometrium. All patients underwent an ultrasound examination with Doppler scanning on the 7th (+1) day after ovulation and endometrial biopsy withfurther histological and immunohistochemical studies: the expression of VEGF, TGF-β, CD 138 markers was determined.Results and discussion. Thus, in patients with chronic atrophic endometritis with impaired microcirculation, sexually transmitted diseases and Asherman's syndrome were more often detected, cycle disorders such as algomenorrhea and hypomenorrhea, and intrauterine intrauterine interventions in anamnesis are typical.Conclusions. According to immunohistochemical studies in patients with hemodynamic disorders, the expression of VEGF is statistically reduced, the expression of TGF-β is increased.
About the Authors
G. Kh. Gazizova
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
A. V. Maslennikov
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
A. G. Yashchuk
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
L. A. Dautova
ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России
Russian Federation
Russian Federation
E. V. Akhmetova
Клинический госпиталь «Мать и дитя»
Russian Federation
Russian Federation
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Review
For citations:
Gazizova G.Kh., Maslennikov A.V., Yashchuk A.G., Dautova L.A., Akhmetova E.V. FEATURES OF HEMODYNAMIC DISORDERS IN ATROPHIC FORM OF CHRONIC ENDOMETRITIS. Bashkortostan Medical Journal. 2022;17(1):18-23. (In Russ.)
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