DEVELOPMENT OF A COMPLEX HERBAL REMEDY FOR THE PREVENTION OF INFLAMMATORY DISEASES OF THE ORAL CAVITY

Abstract

According to WHO, up to 95% of the adult population suffers from inflammatory periodontal diseases. A number of publications describe medicinal plants and preparations based on them that are effective for the treatment of the oral cavity. It has been found that the antimicrobial activity of herbal remedies is of great importance in the treatment of periodontal diseases.The aim was to develop a plant-based remedy with an antimicrobial effect for the treatment of inflammatory diseases of the oral cavity. Material and methods. Based on the literature data, five types of medicinal plant materials were selected and the antimicrobial activity of their alcoholic extracts was analyzed.Results. Three types of medicinal plant materials were selected with the most pronounced zone of microorganism growth inhibition, on the basis of which an agent for the oral cavity (mouth rinse) with the commercial name «Art-Dentale Expert», effective against strains of Staphylococcus aureus and Escherichia coli, was developed and registered. The main active ingredients of the product are extracts of pomegranate pericarp, eucalyptus leaves and thyme herb. «Art-Dentale» rinse showed higher efficiency in comparison with the reference preparations «Stomatofit» and «Rotokan».