RESEARCH OF THE COMPONENT COMPOSITION OF HYDRODISTILLATION PRODUCTS OF LEONURUS DEMINUTUS V.I. KREСZ HERB

Abstract

Purpose is to determine the content of the component composition of Leonurus deminutus V.I. Krecz. herb using the chromatomass spectrometric method.Material and methods. The object of the study was samples of aerial organs of L. deminutus stored in the Irkutsk region in 2020during the blooming period. The studied raw materials were subjected to hydrodistillation according to the method No.1 of OFS 1.1.5.3.0010.15 of the State Pharmacopoeia of the XIV edition, the distillate yield was 0.02±0.001% on dry raw materials. The fractions were analyzed by chromatomass spectrometry on an Agilent Technologies 7890A/7000D (QQQ) device.Results. 19 compounds were identified. Major substances are among sesquiterpene compounds - 3,8,8-trimethyl-1,2,3,4,5,6,7,8-octahydro-2-naphthalenyl methyl acetate (11,09%) and 8-cedren-13-ol (5,36%), hydrocarbons - di(sec-butyl)3,3- dimethylpentanedioate (9,77%), carotenes - β-carotene (4,79%), organic acid esters - diisobutyl phthalate (13,54%), high-molecular fatty acids - trimethylsilyl ether of palmitic acid (14,5%).Conclusions. The composition of the steam distillation of products of the aerial part of L. deminutus growing in the Irkutsk re-gion was studied for the first time.